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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of DNA-templated transcription initiation
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Accession:GO:2000142 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of DNA-templated transcription initiation.
Synonyms:exact_synonym: regulation of DNA-dependent transcription, initiation;   regulation of initiation of DNA-dependent transcription

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regulation of DNA-templated transcription initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RRN3 RRN3 homolog, RNA polymerase I transcription factor acts_upstream_of_or_within ISO (PMID:8413268) MGI PMID:8413268 NCBI chr 5:14,235,368...14,271,790
Ensembl chr 5:14,235,414...14,272,020 		JBrowse link
negative regulation of DNA-templated transcription initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MORC1 MORC family CW-type zinc finger 1 acts_upstream_of_or_within ISO (PMID:25503965) MGI PMID:25503965 NCBI chr22:71,664,183...71,828,879 JBrowse link
G THRA thyroid hormone receptor alpha involved_in ISO (PMID:8524305) UniProt PMID:8524305 NCBI chr16:66,087,071...66,118,137 JBrowse link
G THRA thyroid hormone receptor alpha involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:66,085,067...66,118,079 JBrowse link
negative regulation of RNA polymerase II transcription preinitiation complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMGB1 high mobility group box 1 involved_in ISO (PMID:8006019) UniProt PMID:8006019 NCBI chr 3:9,353,333...9,357,765 JBrowse link
G THRA thyroid hormone receptor alpha involved_in ISO (PMID:8524305) UniProt PMID:8524305 NCBI chr16:66,087,071...66,118,137 JBrowse link
G THRA thyroid hormone receptor alpha involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:66,085,067...66,118,079 JBrowse link
negative regulation of transcription initiation by RNA polymerase II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTNNBIP1 catenin beta interacting protein 1 involved_in ISO (MGI:4821083|PMID:11751639) BHF-UCL PMID:11751639 MGI:4821083 NCBI chr20:121,861,266...121,921,541
Ensembl chr20:121,892,415...121,921,621 		JBrowse link
G HEY2 hes related family bHLH transcription factor with YRPW motif 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:47,965,808...47,977,435
Ensembl chr13:47,964,847...47,977,346 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:122,282,989...122,288,392
Ensembl chr 8:122,282,630...122,288,384 		JBrowse link
G PCID2 PCI domain containing 2 involved_in ISO (MGI:6106288|PMID:29138493) UniProt PMID:29138493 MGI:6106288 NCBI chr 3:91,163,158...91,212,450
Ensembl chr 3:91,177,463...91,211,735 		JBrowse link
G ZNF451 zinc finger protein 451 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:14,434,878...14,516,914
Ensembl chr17:14,433,977...14,516,788 		JBrowse link
G ZNF473 zinc finger protein 473 ISO RGD PMID:12748187 RGD:1299608 NCBI chr 6:43,166,310...43,185,447
Ensembl chr 6:43,165,871...43,187,219 		JBrowse link
positive regulation of DNA-templated transcription initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCLAF1 BCL2 associated transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:37,133,898...37,165,296
Ensembl chr13:37,143,772...37,166,793 		JBrowse link
G CEBPA CCAAT enhancer binding protein alpha involved_in ISO (PMID:28186500) UniProt PMID:28186500 NCBI chr 6:28,342,506...28,345,759
Ensembl chr 6:28,343,907...28,344,977 		JBrowse link
G FOSL1 FOS like 1, AP-1 transcription factor subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:8,356,263...8,365,606
Ensembl chr 1:8,356,836...8,364,918 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit involved_in ISO (PMID:23027619) CACAO PMID:23027619 NCBI chr20:74,204,481...74,207,835
Ensembl chr20:74,205,542...74,206,546 		JBrowse link
G MITF melanocyte inducing transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:30,747,747...30,971,951
Ensembl chr22:30,748,440...30,972,168 		JBrowse link
G SETX senataxin involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:5,773,122...5,872,372
Ensembl chr12:5,773,165...5,875,481 		JBrowse link
G TWIST1 twist family bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:39,040,178...39,042,384
Ensembl chr21:39,040,547...39,041,146 		JBrowse link
positive regulation of RNA polymerase II transcription preinitiation complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHR aryl hydrocarbon receptor acts_upstream_of_or_within ISO (PMID:8215422) MGI PMID:8215422 NCBI chr21:40,778,198...40,826,491
Ensembl chr21:40,778,218...40,826,478 		JBrowse link
G CAND1 cullin associated and neddylation dissociated 1 involved_in ISO PMID:10567521 UniProt PMID:10567521 RGD:8553447 NCBI chr11:62,923,198...62,968,789
Ensembl chr11:62,922,885...62,966,994 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 ISO RGD PMID:16891311 RGD:1625706 NCBI chr10:93,316,774...93,395,187
Ensembl chr10:93,316,840...93,388,832 		JBrowse link
G IKZF1 IKAROS family zinc finger 1 acts_upstream_of_or_within ISO (PMID:21245044) MGI PMID:21245044 NCBI chr21:8,398,902...8,500,431
Ensembl chr21:8,402,719...8,484,723 		JBrowse link
G PSMC6 proteasome 26S subunit, ATPase 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr24:29,784,825...29,807,701
Ensembl chr24:29,784,826...29,807,490 		JBrowse link
G TP53 tumor protein p53 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223 		JBrowse link
G WNT10B Wnt family member 10B acts_upstream_of_or_within ISO (PMID:19056892) MGI PMID:19056892 NCBI chr11:45,205,728...45,229,050
Ensembl chr11:45,205,566...45,210,893 		JBrowse link
positive regulation of transcription initiation by RNA polymerase II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHX36 DEAH-box helicase 36 involved_in ISO (PMID:21993297) UniProt PMID:21993297 NCBI chr15:36,387,242...36,438,133
Ensembl chr15:36,387,228...36,437,606 		JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22323595) Ensembl
MGI		 PMID:22323595 GO_REF:0000107 NCBI chr 6:38,857,067...38,900,177
Ensembl chr 6:38,854,803...38,872,967 		JBrowse link
G GTF2A1 general transcription factor IIA subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:58,506,888...58,552,587
Ensembl chr24:58,506,537...58,551,069 		JBrowse link
G GTF2A2 general transcription factor IIA subunit 2 involved_in ISO (PMID:11030333) ComplexPortal PMID:11030333 NCBI chr26:23,850,483...23,868,477 JBrowse link
G HNF1A HNF1 homeobox A involved_in ISO (PMID:15355349) UniProt PMID:15355349 NCBI chr11:116,334,935...116,358,582
Ensembl chr11:116,335,675...116,357,751 		JBrowse link
G HNF1B HNF1 homeobox B involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:30,033,486...30,097,106
Ensembl chr16:30,036,766...30,097,088 		JBrowse link
G KAT8 lysine acetyltransferase 8 involved_in ISO (PMID:33657400) UniProt PMID:33657400 NCBI chr 5:27,806,082...27,820,832
Ensembl chr 5:27,805,844...27,820,748 		JBrowse link
G LOC103215829 DNA excision repair protein ERCC-6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:42,288,702...42,370,045
Ensembl chr 9:42,288,825...42,373,906 		JBrowse link
G LOC103220209 activated RNA polymerase II transcriptional coactivator p15-like involved_in IEA InterPro GO_REF:0000002 NCBI chr14:46,271,323...46,271,754 JBrowse link
G MED1 mediator complex subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:66,719,393...66,764,902
Ensembl chr16:66,719,423...66,762,896 		JBrowse link
G MED12 mediator complex subunit 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:60,915,796...60,939,220
Ensembl chr  X:60,915,703...60,937,677 		JBrowse link
G MED13 mediator complex subunit 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:33,163,032...33,285,385
Ensembl chr16:33,162,852...33,285,445 		JBrowse link
G MED14 mediator complex subunit 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:37,810,996...37,898,114
Ensembl chr  X:37,810,710...37,897,929 		JBrowse link
G MED16 mediator complex subunit 16 involved_in ISO (PMID:12218053) UniProt PMID:12218053 NCBI chr 6:617,998...638,340 JBrowse link
G MED17 mediator complex subunit 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:85,031,407...85,060,562
Ensembl chr 1:85,031,716...85,059,285 		JBrowse link
G MED24 mediator complex subunit 24 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:66,126,580...66,161,589
Ensembl chr16:66,127,548...66,161,585 		JBrowse link
G MED30 mediator complex subunit 30 involved_in ISO (PMID:12218053) UniProt PMID:12218053 NCBI chr 8:112,162,112...112,181,630
Ensembl chr 8:112,162,149...112,181,585 		JBrowse link
G MED4 mediator complex subunit 4 involved_in ISO (PMID:12218053) UniProt PMID:12218053 NCBI chr 3:25,990,203...26,009,472
Ensembl chr 3:25,990,159...26,009,438 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in ISO (MGI:6377809|PMID:26691508) CACAO PMID:26691508 MGI:6377809 NCBI chr 8:122,282,989...122,288,392
Ensembl chr 8:122,282,630...122,288,384 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:50,589,494...50,711,472
Ensembl chr 7:50,589,856...50,711,498 		JBrowse link
G NFKBIA NFKB inhibitor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:12,211,619...12,216,185
Ensembl chr24:12,210,281...12,214,854 		JBrowse link
G NKX2-5 NK2 homeobox 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:75,391,833...75,399,003
Ensembl chr23:75,391,847...75,395,205 		JBrowse link
G PAXIP1 PAX interacting protein 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr21:123,095,968...123,156,157
Ensembl chr21:123,095,966...123,155,800 		JBrowse link
G POU5F1 POU class 5 homeobox 1 involved_in ISO (MGI:6377809|PMID:26691508) CACAO PMID:26691508 MGI:6377809 NCBI chr17:41,306,523...41,313,065 JBrowse link
G SRF serum response factor involved_in ISO (PMID:8887666) BHF-UCL PMID:8887666 NCBI chr17:28,983,161...28,993,465
Ensembl chr17:28,983,002...28,992,995 		JBrowse link
G SUB1 SUB1 regulator of transcription involved_in IEA InterPro GO_REF:0000002 NCBI chr 4:31,860,744...31,879,851
Ensembl chr 4:31,860,830...31,877,070 		JBrowse link
G TAF1 TATA-box binding protein associated factor 1 involved_in ISO (PMID:17884155) ComplexPortal PMID:17884155 NCBI chr  X:61,167,743...61,269,000
Ensembl chr  X:61,167,589...61,268,839 		JBrowse link
G TAF10 TATA-box binding protein associated factor 10 involved_in ISO (PMID:17884155) ComplexPortal PMID:17884155 NCBI chr 1:58,213,261...58,214,658
Ensembl chr 1:58,213,310...58,214,581 		JBrowse link
G TAF11 TATA-box binding protein associated factor 11 involved_in ISO (PMID:17884155) ComplexPortal PMID:17884155 NCBI chr17:37,230,382...37,241,574 JBrowse link
G TAF12 TATA-box binding protein associated factor 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:104,164,912...104,199,925
Ensembl chr20:104,164,907...104,200,272 		JBrowse link
G TAF13 TATA-box binding protein associated factor 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:24,505,023...24,516,018
Ensembl chr20:24,463,961...24,517,642 		JBrowse link
G TAF2 TATA-box binding protein associated factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:114,291,325...114,395,189
Ensembl chr 8:114,290,866...114,395,537 		JBrowse link
G TAF3 TATA-box binding protein associated factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:7,865,433...8,063,932
Ensembl chr 9:7,865,519...8,063,923 		JBrowse link
G TAF4 TATA-box binding protein associated factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:2,167,585...2,252,383
Ensembl chr 2:2,167,341...2,252,156 		JBrowse link
G TAF4B TATA-box binding protein associated factor 4b involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:54,198,730...54,357,101
Ensembl chr18:54,200,414...54,356,611 		JBrowse link
G TAF5 TATA-box binding protein associated factor 5 involved_in ISO (PMID:17884155) ComplexPortal PMID:17884155 NCBI chr 9:96,411,690...96,432,668 JBrowse link
G TAF5 TATA-box binding protein associated factor 5 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 9:96,412,242...96,433,481 JBrowse link
G TAF6 TATA-box binding protein associated factor 6 involved_in ISO (PMID:11583621), (PMID:17884155), (PMID:18628956) UniProt PMID:11583621 PMID:17884155 PMID:18628956 NCBI chr28:12,958,555...12,971,100
Ensembl chr28:12,963,609...12,973,368 		JBrowse link
G TAF7 TATA-box binding protein associated factor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:43,938,202...43,940,486
Ensembl chr23:43,938,714...43,939,763 		JBrowse link
G TAF8 TATA-box binding protein associated factor 8 involved_in ISO (PMID:17884155) ComplexPortal PMID:17884155 NCBI chr17:30,065,086...30,105,653 JBrowse link
G TAF8 TATA-box binding protein associated factor 8 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr17:30,079,467...30,105,596 JBrowse link
G TAF9 TATA-box binding protein associated factor 9 involved_in ISO (PMID:17884155) ComplexPortal PMID:17884155 NCBI chr 4:65,451,038...65,455,896 JBrowse link
G TBP TATA-box binding protein involved_in ISO (PMID:17884155) ComplexPortal PMID:17884155 NCBI chr13:97,661,905...97,678,640
Ensembl chr13:97,660,864...97,681,497 		JBrowse link
G XPA XPA, DNA damage recognition and repair factor acts_upstream_of_or_within ISO (PMID:22323595) MGI PMID:22323595 NCBI chr12:41,711,872...41,735,024
Ensembl chr12:41,711,943...41,725,698 		JBrowse link
G ZNHIT1 zinc finger HIT-type containing 1 involved_in ISO (MGI:6106288|PMID:29138493) UniProt PMID:29138493 MGI:6106288 NCBI chr28:11,955,822...11,962,304
Ensembl chr28:11,955,521...11,962,195 		JBrowse link
regulation of RNA polymerase II transcription preinitiation complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF7IP activating transcription factor 7 interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:14,264,795...14,397,062
Ensembl chr11:14,264,706...14,392,206 		JBrowse link
regulation of transcription initiation by RNA polymerase II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXO1 forkhead box O1 involved_in ISO PMID:19483080 UniProt PMID:19483080 RGD:401901209 NCBI chr 3:18,916,849...19,027,776
Ensembl chr 3:18,920,651...19,027,707 		JBrowse link
regulation of transcriptional start site selection at RNA polymerase II promoter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PWWP2A PWWP domain containing 2A involved_in ISO (MGI:6867108|PMID:33235983) UniProt PMID:33235983 MGI:6867108 NCBI chr23:62,428,936...62,490,904
Ensembl chr23:62,460,139...62,490,803 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16919
    metabolic process 10498
      organic substance metabolic process 10049
        macromolecule metabolic process 8467
          macromolecule biosynthetic process 6536
            RNA biosynthetic process 3222
              DNA-templated transcription initiation 180
                regulation of DNA-templated transcription initiation 72
                  negative regulation of DNA-templated transcription initiation + 10
                  positive regulation of DNA-templated transcription initiation + 59
                  regulation of transcription initiation by RNA polymerase I 0
                  regulation of transcription initiation by RNA polymerase II + 63
Path 2
Term Annotations click to browse term
  biological_process 16919
    metabolic process 10498
      organic substance metabolic process 10049
        organic cyclic compound metabolic process 5668
          nucleobase-containing compound metabolic process 5214
            nucleic acid metabolic process 4702
              RNA metabolic process 4146
                RNA biosynthetic process 3222
                  regulation of RNA biosynthetic process 3085
                    regulation of DNA-templated transcription 3070
                      regulation of DNA-templated transcription initiation 72
                        negative regulation of DNA-templated transcription initiation + 10
                        positive regulation of DNA-templated transcription initiation + 59
                        regulation of transcription initiation by RNA polymerase I 0
                        regulation of transcription initiation by RNA polymerase II + 63
paths to the root